Symbol
Name
ID

Taf4b
TATA-box binding protein associated factor 4b
MGI:2152345

Phenotype annotations related to reproductive system

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Azoospermia	Male infertility
Disease(s) Associated with TAF4B	Azoospermia	Male infertility
spermatogenic failure 13

Mouse Phenotypes

abnormal oocyte morphology

decreased oocyte number

oligozoospermia

abnormal acrosome assembly

decreased male germ cell number

increased granulosa cell apoptosis

asthenozoospermia

decreased granulosa cell proliferation

abnormal spermatogonia proliferation

absent mature ovarian follicles

decreased primordial ovarian follicle number

decreased secondary ovarian follicle number

abnormal tertiary ovarian follicle number

decreased tertiary ovarian follicle number

absent ovarian follicles

increased atretic ovarian follicle number

impaired ovarian folliculogenesis

small ovary

ovary cyst

ovary degeneration

seminiferous tubule degeneration

increased Leydig cell number

decreased testis weight

small testis

premature ovarian failure

early reproductive senescence

abnormal spermatogenesis

abnormal spermiogenesis

early sexual maturation

abnormal superovulation

abnormal estrous cycle

prolonged estrus

female infertility

male infertility

Availability

Mouse Genotype

Taf4b^tm1Rtj/Taf4b^tm1Rtj

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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